Railroad personnel were frequently surrounded by harmful chemicals that significantly increased the risk of multiple cancers over time.
Particularly diesel exhaust exposure, carrying substances like PAHs and benzene, has been shown to elevate the likelihood of developing lung cancer, with studies quantifying added risk in rail-heavy occupations.
Besides lung cancer, exposures in the industry have also been associated with elevated rates of bladder cancer, kidney cancer, colon cancer, and throat or laryngeal cancer, often linked to fuel handling, creosote-treated ties, and solvent use.
Blood-related malignancies, including acute myeloid leukemia, multiple myeloma, and other leukemias, have been tied to chronic exposure to diesel fumes and marrow-toxic chemicals.
Mesothelioma, a cancer of the lining of the lungs, has also appeared frequently among shop workers and maintenance crews exposed to asbestos in brake shoes, insulation, and electrical components.
These findings reflect a pattern of prolonged exposure that contributed to increased cancer risk across multiple disease types.
Cancer types potentially linked to railroad work include:
- Lung cancer – solid evidence from diesel exhaust exposures; significantly elevated rates have been noted in long-term railroad workers
- Bladder cancer – associated with exposure to solvents and combustion by-products present in diesel fumes and creosote
- Kidney cancer – linked to solvents, creosote, and possibly heavy metals encountered in shop environments
- Colon cancer, intestinal cancer and stomach cancer – gastrointestinal cancers observed at elevated rates among railroad staff with chemical and diesel exposure
- Laryngeal (throat) cancer – tied to inhaling asbestos, PAHs, metal fumes, and diesel particulates, particularly among shop and engine crews
- Multiple myeloma – associated with solvent and chemical exposures that impact bone marrow and immune function
- Acute myeloid leukemia (AML) – linked to prolonged exposure to benzene and exhaust components that damage marrow cells
- Mesothelioma – strongly tied to occupational asbestos exposure, prevalent in braking systems, insulation, and older equipment
- Esophageal cancer – associated with long-term diesel exhaust, PAHs, solvents, and asbestos exposure.
- Neck cancers beyond throat – inhalation of asbestos fibers, diesel particulates, and welding fumes can also affect tissues higher in the airway.
- Chronic lymphocytic leukemia (CLL) and other blood cancers – tied to benzene and solvent exposures.
- Non-Hodgkin’s lymphoma and Hodgkin lymphoma – strongly associated with benzene, herbicides, PCBs, and solvents.
- Skin cancers (including melanoma) – linked to creosote and PAH-rich products used on railroad ties and bridges.
- Pancreatic cancer – limited but emerging evidence connects diesel exhaust exposure to higher risks.
- Prostate cancer – some occupational studies suggest higher rates among workers exposed to diesel exhaust and metalworking fluids.
- Brain and central nervous system cancers – rare but occasionally reported in worker studies, possibly linked to solvent and hydrocarbon exposures.
How Does One Prove their Cancer Diagnosis is Linked to Railroad Work?
Proving that a cancer diagnosis is tied to railroad employment requires showing how workplace exposures contributed to the disease.
Many affected workers held railroad jobs where exposures occurred daily, such as exposure to diesel exhaust, asbestos, benzene, and other hazardous substances.
Medical evidence is central, so attorneys collect medical records that confirm the type of cancer and connect it to recognized occupational carcinogens.
Witness statements from coworkers are also valuable, as they can describe unsafe conditions and routine contact with dangerous materials.
Demonstrating an elevated risk involves linking these exposures to established scientific studies and regulatory findings that confirm their role in specific cancer diagnoses.
This connection builds the foundation for filing a FELA claim, since the law requires showing that railroad negligence contributed to unsafe working conditions.
An experienced lawyer will often consult with medical and occupational experts to strengthen the causal chain between job duties and disease.
Together, this evidence forms a compelling case that the cancer was not random, but the direct result of preventable conditions in the railroad industry.